The verdict
If you are a SaaS company and your emails should follow sign-ups, activation and cancellation, I'd pick Loops. One contact record then drives onboarding, lifecycle and transactional email.
If you are an agency, a services business or a small team that sends newsletters and campaigns and wants them to look right, I'd pick Campaign Monitor.
Loops needs clean events from your product, so budget engineering time before you move over. Campaign Monitor needs none, but it will not react to product behaviour on its own. If you want cold outreach, neither fits.